Mr Simon a Cudlip MBBS BSc(Hons) MD FRCS FRCS(SN)

Consultant Neurosurgeon and Spinal Surgeon

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Biography

Simon Cudlip is currently in post as a consultant neurosurgeon and is head of the department of neurosurgery at the John Radcliffe Hospital, Oxford having been originally appointed in 2004. Immediately prior to this he had completed a 1 year fellowship in pituitary surgery at the NHNNS, Queen Square. The  consultant appointment in Oxford was made to replace the position held by Mr Christopher Adams, and specifically, to continue the internationally recognized pituitary practice Mr Adams had established over the previous decades.

 

Innovations by Mr Cudlip at the Oxford University Hospitals NHS Trust have included the development of a endoscopically assisted minimally invasive technique for spinal surgery allowing day-case surgery, the first implantation of a cervical disc replacement in the region (now widely adopted), the joint development of endoscopically assisted transcranial tumour resection for glioma led by Mr Plaha, and initiating a novel minimally invasive approach for brain tumours via an incision in the eyebrow.

 

Since 2004 the transition has been made to a pure endoscopic surgical technique for pituitary and anterior skullbase disease, a 48 hour hospital stay for patients undergoing pituitary surgery, a weekly joint pituitary clinic and closer working with the endocrine team, and satellite joint pituitary clinics. From the time of Mr Cudlip’s appointment, the number of pituitary cases operated on per year has nearly doubled to over 100-120 cases/ year. Expansion of the endonasal/ endoscopic technique has allowed more complex tumours to be approached, and now this technique is used for paediatric cases, skull base meningioma, chordoma/ chondrosarcoma, and craniopharyngioma. As a result successful funding has been gained for a dedicated image guidance system, two HD endoscopic systems and 4 full sets of instruments. Mr Cudlip has now performed over 1000 operations for pituitary disease.

 

Together with the academic department of endocrinology, a number of clinically based publications have led to changes in practice in the management of patients with pituitary disease internationally.

 

The size and experience of the pituitary practice has allowed the establishment of a internationally recognized post-CCT endoscopic surgical fellowship supervised by Mr Cudlip. This position is now also recognized as the sole accredited Royal College of Surgeons of England fellowship in pituitary surgery.

 

Mr Cudlip is regularly invited to lecture on the subject of pituitary surgery, is a surgical tutor at the Royal College of Surgeons, runs an international clinical course on cervical arthroplasty in Oxford and Amsterdam, is a member of the panel at the yearly Royal College of Physicians pituitary conference, and recently has become a member of the Specialist Endocrinology Clinical Reference Group.

 

Mr Cudlip travels every year to Tashkent in Uzbekistan and Kerala to perform operations and see patients in clinic Pro Bono, and to help support and educate local surgeons.

 

Mr Cudlip recently undertook a series of lectures in China, speaking as an invited lecturer at a joint meeting between the two largest neurosurgical departments in China.

 

Some recent scientific publications:

1: Pereira EAC, Grandidge CA, Nowak VA, Cudlip SA. Cerebrospinal fluid leaks
after transsphenoidal surgery - Effect of a polyethylene glycol hydrogel dural
sealant. J Clin Neurosci. 2017 Oct;44:6-10. doi: 10.1016/j.jocn.2017.06.016. Epub
2017 Jul 1. Review. PubMed PMID: 28676314.


2: Tampourlou M, Ntali G, Ahmed S, Arlt W, Ayuk J, Byrne JV, Chavda S, Cudlip S, 
Gittoes N, Grossman A, Mitchell R, O'Reilly MW, Paluzzi A, Toogood A, Wass JAH,
Karavitaki N. Outcome of Nonfunctioning Pituitary Adenomas That Regrow After
Primary Treatment: A Study From Two Large UK Centers. J Clin Endocrinol Metab.
2017 Jun 1;102(6):1889-1897. doi: 10.1210/jc.2016-4061. PubMed PMID: 28323946.


3: Surchi H, Jafar-Mohammadi B, Pal A, Cudlip S, Grossman AB. Local optometrists
are a major source of referrals to a pituitary tumour clinic. Endocr Relat
Cancer. 2017 May;24(5):L33-L34. doi: 10.1530/ERC-17-0034. Epub 2017 Mar 1. PubMed
PMID: 28249962.


4: Sbardella E, Joseph RN, Jafar-Mohammadi B, Isidori AM, Cudlip S, Grossman AB. 
Pituitary stalk thickening: the role of an innovative MRI imaging analysis which
may assist in determining clinical management. Eur J Endocrinol. 2016
Oct;175(4):255-63. doi: 10.1530/EJE-16-0455. Epub 2016 Jul 14. PubMed PMID:
27418059.


5: Ntali G, Capatina C, Fazal-Sanderson V, Byrne JV, Cudlip S, Grossman AB, Wass
JA, Karavitaki N. Mortality in patients with non-functioning pituitary adenoma is
increased: systematic analysis of 546 cases with long follow-up. Eur J
Endocrinol. 2016 Feb;174(2):137-45. doi: 10.1530/EJE-15-0967. Epub 2015 Nov 6.
PubMed PMID: 26546611.


6: Plaha P, Livermore LJ, Voets N, Pereira E, Cudlip S. Minimally invasive
endoscopic resection of intraparenchymal brain tumors. World Neurosurg. 2014
Dec;82(6):1198-208. doi: 10.1016/j.wneu.2014.07.034. Epub 2014 Jul 29. PubMed
PMID: 25084167.


7: Preda V, Korbonits M, Cudlip S, Karavitaki N, Grossman AB. Low rate of
germline AIP mutations in patients with apparently sporadic pituitary adenomas
before the age of 40: a single-centre adult cohort. Eur J Endocrinol. 2014
Nov;171(5):659-66. doi: 10.1530/EJE-14-0426. Epub 2014 Sep 2. PubMed PMID:
25184284.